With help from a test from Madison-based Exact Sciences, tens of thousands more breast cancer patients may be able to safely forgo chemotherapy, according to a study published this month in the New England Journal of Medicine. The study, called RxPONDER, was led by the independent SWOG Cancer Research Network and sponsored by the National Cancer Institute.

The results further an ongoing effort to replace a “one-size-fits-all approach” with cancer treatment personalized to each patient and tumor, said lead author Dr. Kevin Kalinsky, a SWOG investigator and director of the Glenn Family Breast Center at the Winship Cancer Institute of Emory University in a press release.

Since 2007, studies have shown that the Oncotype DX Breast Recurrence Score test, which analyzes 21 genes in breast cancer tumors, can be used to assess not only the likelihood that a patient’s cancer will recur, but also the likelihood that the cancer will respond to chemotherapy. That information can save patients from undergoing the treatment — and its harsh side effects — unnecessarily.

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