Nearly 81% of adults who got a high dose of Madison-based FluGen’s experimental flu vaccine in a study had a broad immune response and 71% had a significant response to a particular flu protein, the company reported Wednesday.

The findings, published in the Journal of Infectious Diseases, come as FluGen continues other studies of older adults and children who are receiving the vaccine, known as M2SR, which uses a self-limiting version of the influenza virus.

The company, based on research by UW-Madison scientists Yoshihiro Kawaoka and Gabriele Neumann, is raising money and exploring relationships with large drug companies to conduct larger studies that could lead to approval of its intranasal vaccine within four years, its leader said.

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